Glutathione is a tripeptide (containing 3 amino acids: cysteine, glutamic acid, and glycine) naturally made in human cells that functions as a powerful antioxidant. It plays an important role in detoxification. In compounding, Glutathione may be prepared as an injectable formulation when prescribed by a licensed healthcare provider.
Glutathione is available in oral supplement form but has less than 1% bioavailability. Being a peptide, Glutathione is prone to enzymatic degradation and poor gastrointestinal absorption. Some providers may prescribe compounded Glutathione injections when they determine that an injectable route is more appropriate for an individual patient’s needs.
While there are no large randomized controlled studies, some common side effects reported include injection-site reactions (pain, erythema, swelling), headache, nausea, diarrhea, and rare hypersensitivity reactions. Glutathione may reduce melanin production, which could result in lightening of the skin. Providers should assess patient tolerance and discontinue use if adverse reactions occur.
Contraindications and precautions: Use caution in patients with a history of asthma, sulfite sensitivity, or known allergy to glutathione or any formulation components. Safety data for injectable glutathione during pregnancy and lactation are limited; therefore, use should be avoided in these populations.
Injectable glutathione is not FDA-approved for any indication. When used, it is typically obtained from a compounding pharmacy and prescribed for off-label use.
Administration should occur only under the supervision of a licensed healthcare professional with appropriate patient evaluation, documentation, and informed consent.
Glutathione is primarily produced in the liver, with smaller amounts synthesized in other cells throughout the body. Supplementation can be administered either orally or by injection. Glutathione has poor oral bioavailability, which may lead some individuals to prefer compounded injectable forms.
There are no approved dosages or regimens for using Glutathione, but the following are common dose ranges:
Subcutaneous Glutathione:
Intramuscular Glutathione:
Injectable Glutathione should be stored in the fridge from 36°F to 46°F. It will have a beyond-use date of approximately one month after the patient receives it and should be used within 28 days after the first vial puncture.
Glutathione is not likely to be covered by insurance plans. Injectable Glutathione is compounded from a bulk drug powder, which is often excluded from most insurance’s prescription drug plans.
Medivera Compounding Pharmacy has a staff of trained pharmacists eager to discuss Glutathione or any other medications with you or your staff. They can address any questions you may have regarding dosing, storage, shipping, or any other matter you need assistance with.
Our pharmacy takes pride in providing excellent customer service. When we receive a prescription, our pharmacy team will contact the patient to arrange pick-up or delivery and have a pharmacist discuss the use of each medication. You can count on Medivera to accurately and quickly take care of your patients’ needs.
Our team is ready to help with any questions you may have on starting your patients on Glutathione or any other medication. We can also help in transitioning patients over from different pharmacies. Contact us today to address your questions and help your patients begin their journey to improved health.
Disclaimer: Glutathione is a custom-compounded drug product. Compounded medications are prepared at the direction of a healthcare provider and are not approved by the FDA.
This document is provided as a response to solicited questions about the use of Glutathione.
Glutathione Injection 200mg/mL, 30mL vial
Compounded Glutathione may be administered by subcutaneous or intramuscular injection. The dosing schedule is typically once or twice a week, as recommended by your healthcare provider.
Store Glutathione injections in a refrigerator at a temperature between 36°F and 46°F.
The individual components of this compound play roles in various biological processes:
Cysteine: A sulfur-containing amino acid that serves as a rate-limiting precursor for glutathione synthesis.
Glutamic Acid: An amino acid that acts as a key neurotransmitter and a structural component of the glutathione molecule.
Glycine: The simplest amino acid, which contributes to the formation of proteins and the stabilization of the tripeptide structure.
In compounding, Glutathione may be prepared as a sterile injectable by MediVera Compounding Pharmacy™ when a licensed healthcare provider determines a patient-specific need.
Glutathione is available in oral supplement form but has minimal bioavailability. Being a peptide, Glutathione is prone to enzymatic degradation and poor gastrointestinal absorption. Some providers may prescribe compounded Glutathione injections when they determine that an injectable route is more appropriate for an individual patient’s needs.
Compounded Glutathione may be administered by subcutaneous or intramuscular injection. The dosing schedule is typically once or twice a week, as recommended by your healthcare provider.
Most insurance plans do not cover compounded medications made from bulk drug substances, including compounded Glutathione. Patients should confirm coverage directly with their insurance provider.
Possible side effects of a Glutathione injection include:
Contact your prescriber if you notice persistent or severe reactions, especially at the injection site.
Compounded Lipo-C should be stored in the fridge from 36°F to 46°F.
Glutathione preparations generally have a beyond-use date of about 30 days from the date dispensed. Always check your prescription label for the exact date. Each vial typically contains multiple doses and should be discarded 28 days after first puncture.
Some patients may experience mild discomfort at the injection site, though tolerance varies by individual.
Response to compounded Glutathione varies among patients. Your healthcare provider will monitor progress and make any necessary adjustments to therapy.
Providers can easily prescribe by:
• FAX: Submit a Fax Request Form to get started
• EMR: Submit prescriptions directly through your EMR system.
• Phone: Call us at 877-531-1147 to speak with our team and place your prescription.
• Provider Portal: Use our Provider Portal for quick and convenient online prescribing.
If you have any further questions, contact us at [email protected].
*Compounded medications are prepared based on a healthcare provider’s prescription to meet individual patient needs. These medications are not FDA-approved, and no claims are made regarding their safety, efficacy, or quality. While we offer compounded medications tailored to individual needs, we also have commercially available drugs for patients when appropriate. All doses listed are common doses; customized medication strengths are also available as prescribed by a licensed provider
Download the Product Catalog: Explore our range of personalized medications and solutions.
Submit Your Patient's Prescription: Send via phone, fax, e-scribe, or sign up for our convenient Provider Portal.
Get Assigned a Local Representative: Fill out a provider portal form and we will connect you with a local representative.
Request a Valid Prescription: Obtain a prescription from your doctor.
Transfer a Prescription: Request for one of our pharmacists to call your doctor or current pharmacy
Refill a Prescription: Easily refill your prescription by downloading our convenient app.
We'll Contact You: Expect a call within 24 hours after we receive your prescription.
Fast Shipping: Most compounds are shipped within 48 hours of patient confirmation.
This pharmacy is FANTASTIC! They are professional and will help you understand and educate as needed. I had an order which my doctor forgot to prescribe in a pump, and gave me syringes. They were more than happy to convert my medication. They are professional and well informed!
Fast refills and beat everyone’s price for the supposedly really difficult drug to get! [Another pharmacy] wanted to charge me $4000 per month, here they make it for me for $65 per month. Friendly and clean place.
MediVera Compounding Pharmacy™ is a bit of a drive for me, but I wouldn’t get my meds anywhere else! They offer excellent customer service and affordable prices. I recently started seeing a new doctor who is over an hour away. He asked if I had a pharmacy that I wanted him to send my prescription to, and when I told him University, he said that he recommends them to everyone because of their low cost and expertise! I was pleasantly surprised that he knew about this place because it’s nowhere near his office. It really boosted my confidence in their work.
Been using them as my primary compounder for my patients for going on four years and they will always be my first choice. I love what they stand for, they really support the integrative and functional medicine community beyond their own business.
Wish you were as happy with your compounding pharmacy as they are? Give us a call today and discover for yourself what MediVera Compounding Pharmacy™ can do for you.
Call Today!
